Proteins and lipids of glycosomal membranes from Leishmania tarentolae and Trypanosoma brucei
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Proteins and lipids of glycosomal membranes from Leishmania tarentolae and Trypanosoma brucei
In kinetoplastid protists, several metabolic pathways, including glycolysis and purine salvage, are located in glycosomes, which are microbodies that are evolutionarily related to peroxisomes. With the exception of some potential transporters for fatty acids, and one member of the mitochondrial carrier protein family, proteins that transport metabolites across the glycosomal membrane have yet t...
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In eukaryotic evolution, the earliest branch of organisms to have mitochondria are the trypanosomatids. Their mitochondrial biogenesis not only includes import of most proteins, but also, unlike in other organisms, import of the whole set of tRNAs. In order to investigate these processes, we devised novel procedures for the isolation of mitochondria from two trypanosomatid species: Trypanosoma ...
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The study of RNA editing and other molecular processes in the trypanosome mitochondrion would benefit greatly from the ability to insert and express exogenous DNA in the organelle. However, even with a method to introduce DNA, the current lack of knowledge about mitochondrial transcription would hinder efforts to obtain expression. To circumvent this problem, Leishmania tarentolae promastigotes...
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Taxonomic studies and classification of Leishmania species have developed rapidly in recent years, but controversy still surrounds the relationships between those species infecting lizards and those infecting mammals. Some authorities maintain that the leishmanias o f lizards form a sufficiently distinct group to be ranked as a separate genus - Sauroleishmania(1,2) - while Wallbanks et al. have...
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On the basis of the unsaturated fatty acids which they synthesize, protists can be grouped in a meaningful way. Thus, the unsaturated fatty acids of the true slime mold are identical with the unsaturated fatty acids of the soil amoebae Acanthumoeba and Hartmannella but have no resemblance to those of the cellular slime mold Dictyostelium. Among the zooflagellates, Leishmania enriettii and Leish...
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ژورنال
عنوان ژورنال: F1000Research
سال: 2013
ISSN: 2046-1402
DOI: 10.3410/f1000research.2-27.v1